Try This Irresistible Meat Lovers Pizza Casserole Recipe Today

Crafting an incredible meat lovers pizza casserole brings pure comfort to your dinner table.

Cheese and hearty meats combine in one mouthwatering dish that satisfies deep hunger pangs.

Layers of savory ingredients create a delightful culinary experience that feels like a weekend celebration.

Pepperoni, sausage, and bacon meld together with melted cheese and crispy crust edges.

Each bite promises a flavor explosion that will make you swoon with delight.

Weeknight meals just got an exciting upgrade with this crowd-pleasing recipe.

Reasons to Try Ultimate Meat Lovers Pizza Casserole

  • Indulge in Meaty Comfort: A hearty casserole packed with multiple protein sources that satisfies serious meat lovers from the first bite.
  • Customize with Ease: Flexible recipe allows quick ingredient swaps or additions based on personal preferences and pantry availability.
  • Family-Friendly Feast: Kids and adults will adore this crowd-pleasing dish that combines pizza flavors with classic casserole comfort, making mealtime exciting and delicious.
  • One-Pan Simplicity: Minimal kitchen cleanup with a single baking dish, reducing post-meal washing and saving precious time for enjoying the meal together.

Ingredients Needed for Ultimate Meat Lovers Pizza Casserole

Meat and Pasta:
  • Ground Beef: A protein-packed base that adds rich flavor to the casserole.
  • Italian Sausage: Brings a spicy and savory element to the meat mixture.
  • Pasta: Provides a hearty foundation for the casserole.
  • Pepperoni: Adds classic pizza flavor and a slight spicy kick.
  • Bacon: Contributes a smoky and crispy texture to the dish.
Cheese and Dairy:
  • Mozzarella Cheese, Cheddar Cheese: Create a gooey, melty topping that gives the casserole its classic pizza-like appeal.
Seasonings and Sauce:
  • Garlic Powder: Enhances the overall savory flavor of the meat.
  • Italian Seasoning: Provides a blend of herbs that complement the pizza-inspired dish.
  • Pizza Sauce: Brings the traditional pizza taste to the casserole.
  • Black Olives: Optional garnish that adds a tangy, briny flavor.
  • Red Pepper Flakes: Optional topping for those who enjoy a spicy kick.

Stepwise Preparation for Meat Lovers Pizza Casserole

Step 1: Boil Pasta

Grab your favorite pasta and cook it in a pot of boiling water until it reaches that perfect al dente texture. Once done, drain the water and set the pasta aside, ready for its cheesy adventure.

Step 2: Sizzle the Meats

Heat up a large skillet and toss in ground beef and Italian sausage. Cook these protein powerhouses until they’re beautifully browned.

Drain away any extra grease, then jazz up the meat with a sprinkle of garlic powder, Italian seasoning, and a generous splash of pizza sauce.

Step 3: Layer the Flavor Explosion

Crank the oven to 375°F (190°C).

Grab a 9×13-inch baking dish and give it a quick spray of cooking oil. Now, let’s build some deliciousness:
  • First layer of pasta
  • Half the meat mixture
  • Pepperoni slices
  • Crispy bacon bits
  • Mozzarella cheese
  • Cheddar cheese

Repeat these layers one more time, making sure to finish with a glorious blanket of melty cheese on top.

Step 4: Bake to Perfection

Slide the dish into the oven and bake uncovered for 20-25 minutes. You’re looking for that magical moment when the cheese turns golden and bubbly.

For extra pizzazz, sprinkle some black olives and red pepper flakes on top. Let it cool for a few minutes, then dig in and enjoy your meaty, cheesy masterpiece!

Helpful Tips for Ultimate Meat Lovers Pizza Casserole

  • Cook pasta just until al dente to prevent mushiness when baking, ensuring a perfectly textured casserole.
  • Thoroughly drain excess grease from ground beef and sausage to keep the dish from becoming oily and maintain a rich, clean flavor.
  • Use a mix of mozzarella and cheddar for maximum flavor and optimal melting, creating a gooey, irresistible cheese layer.
  • Adjust red pepper flakes and add extra Italian seasoning to personalize the heat and flavor profile to your taste preferences.
  • Prepare the casserole in advance and refrigerate, then bake when ready to serve for an easy, convenient meal option.

Flavor Variations for Meat Lovers Pizza Casserole

  • Veggie Lover's Version: Replace ground beef and sausage with mixed roasted vegetables like zucchini, bell peppers, mushrooms, and eggplant. Add spinach and use plant-based cheese for a hearty vegetarian alternative.
  • Spicy Southwest Style: Swap Italian seasoning for taco seasoning. Use ground turkey or chicken. Add jalapeños, black beans, and swap mozzarella for pepper jack cheese. Top with fresh cilantro and salsa.
  • Mediterranean Fusion: Incorporate crumbled feta cheese, diced kalamata olives, and ground lamb. Replace pizza sauce with marinara. Sprinkle dried oregano and fresh basil. Garnish with chopped parsley for bright flavors.
  • Pair with Bold Red Wine: Select a robust Chianti or Cabernet Sauvignon that matches the rich meat flavors, cutting through the cheese's creaminess and complementing the spicy pepperoni undertones.
  • Serve with Crisp Caesar Salad: Create a refreshing side with romaine lettuce, parmesan shavings, and tangy dressing to balance the casserole's hearty and dense texture, providing a light counterpoint.
  • Enhance with Garlic Bread: Toast crusty Italian bread with herb-infused butter and garlic, offering a crunchy accompaniment that absorbs the casserole's savory meat sauce and adds textural contrast.

Proper Storage for Meat Lovers Pizza Casserole Leftovers

  • Store leftovers in an airtight container within 2 hours of cooking. Keep in the refrigerator for up to 3-4 days, ensuring the container is sealed tightly to maintain freshness and prevent bacterial growth.
  • Transfer cooled casserole to a freezer-safe dish with a tight-fitting lid. Wrap securely with plastic wrap and aluminum foil. Freeze for up to 2-3 months. Label the container with the date and contents.
  • Place individual portions on a microwave-safe plate. Cover with a damp paper towel to prevent drying. Heat on medium power for 1-2 minutes, stirring halfway through. Check internal temperature reaches 165°F for food safety.

FAQs

  • What meats are used in this casserole?

The casserole features ground beef, Italian sausage, pepperoni, and bacon, creating a protein-packed dish that satisfies serious meat lovers.

  • Can I make this recipe ahead of time?

Yes, you can prepare the casserole in advance and refrigerate it before baking. Just add an extra 510 minutes to the baking time if cooking directly from the refrigerator.

  • Is this dish kid-friendly?

Absolutely! The combination of pasta, cheese, and familiar meats makes this casserole a hit with children and adults alike. The flavors are mild enough for kids but delicious for everyone.

  • What type of cheese works best in this recipe?

Mozzarella and cheddar are recommended, but you can also use provolone or a blend of Italian cheeses for added flavor complexity.

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Amazing Ultimate Meat Lovers Pizza Casserole Recipe


5 Stars 4 Stars 3 Stars 2 Stars 1 Star

4.9 from 32 reviews

  • Total Time: 45 minutes
  • Yield: 6 1x

Description

Meat lovers pizza casserole delivers a hearty culinary symphony of pepperoni, sausage, and melted cheese in one incredible dish. Packed with robust flavors and guaranteed to satisfy serious pizza cravings, you’ll devour every delicious, comforting bite.


Ingredients

Scale

Meats:

  • 1 pound ground beef
  • 0.5 pound Italian sausage
  • 0.5 cup pepperoni slices
  • 0.5 cup cooked bacon, crumbled

Cheeses:

  • 2 cups shredded mozzarella cheese
  • 0.5 cup shredded cheddar cheese

Other Ingredients:

  • 12 ounces (340 grams) pasta (penne or rotini)
  • 2 cups pizza sauce
  • 1 teaspoon garlic powder
  • 1 teaspoon Italian seasoning
  • 0.25 cup black olives (optional)
  • 0.25 teaspoon red pepper flakes (optional)

Instructions

  1. Prepare the pasta by boiling in salted water until perfectly tender, approximately 8-10 minutes. Thoroughly drain and set aside.
  2. Heat a large skillet over medium-high temperature. Crumble ground beef and Italian sausage, cooking until completely browned and no pink remains. Eliminate excess fat through thorough draining.
  3. Enhance the meat mixture by incorporating garlic powder, Italian seasoning, and pizza sauce. Stir until ingredients are evenly distributed and flavors meld together.
  4. Preheat the oven to 375°F (190°C), ensuring even heat distribution. Generously grease a 9×13-inch baking dish to prevent sticking.
  5. Create the first layer by spreading half the cooked pasta across the bottom of the dish. Top with half the seasoned meat mixture, distributing evenly.
  6. Arrange a layer of pepperoni and crispy bacon pieces over the meat. Sprinkle generously with mozzarella and cheddar cheese.
  7. Repeat the layering process: remaining pasta, meat mixture, pepperoni, bacon, and finish with a final abundant cheese topping.
  8. Transfer the casserole to the preheated oven. Bake uncovered for 20-25 minutes until cheese becomes golden, melted, and slightly bubbling.
  9. Optional: Garnish with sliced black olives and red pepper flakes for additional flavor and visual appeal. Allow the casserole to rest for 5 minutes before serving to help set the layers.

Notes

  • Customize meat selection by using ground turkey or chicken for a leaner version that still packs flavor.
  • Prep ingredients ahead of time to make assembly quick and streamlined during busy weeknights.
  • Swap traditional pasta with gluten-free alternatives for those with dietary restrictions, ensuring everyone can enjoy this hearty dish.
  • Prep Time: 20 minutes
  • Cook Time: 25 minutes
  • Category: Lunch, Dinner, Appetizer, Snacks
  • Method: Boiling
  • Cuisine: Italian-American

Nutrition

  • Serving Size: 6
  • Calories: 1054 kcal
  • Sugar: 3 g
  • Sodium: 1370 mg
  • Fat: 79 g
  • Saturated Fat: 31 g
  • Unsaturated Fat: 40 g
  • Trans Fat: 1 g
  • Carbohydrates: 44 g
  • Fiber: 3 g
  • Protein: 63 g
  • Cholesterol: 140 mg
Nate Harper

Nate Harper

Founder & Recipe Curator

Expertise

Single-Recipe Development, Farm-to-Table Cooking, Seasonal Menu Planning, Culinary Storytelling, Home Kitchen Innovation

Education

Cascade Culinary Institute – Central Oregon Community College
Certificate in Culinary Arts

Focus: Farm-to-table cuisine, sustainable cooking practices, and seasonal recipe creation.

Nate studied under experienced chefs who emphasized local sourcing, minimal waste, and building recipes from fresh, simple ingredients.


Nate Harper is the founder and creative force behind Make, Take, Bake. Raised in the wild beauty of Oregon’s high desert, Nate grew up surrounded by family gardens, farmers’ markets, and home kitchens that celebrated the seasons.
His early love for simple, honest food evolved into a professional passion when he attended Cascade Culinary Institute, where he sharpened his skills in creating recipes that are sustainable, satisfying, and made for everyday life.
Nate’s goal is to make cooking feel accessible, free of fuss, and full of flavor. He believes a single, thoughtfully built dish can stand alone, and sometimes even steal the show.

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