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Pepperoni Pizza Casserole Recipe

Pepperoni Pizza Casserole Recipe


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4.7 from 23 reviews

  • Total Time: 55 minutes
  • Yield: 6 1x

Description

Hearty pepperoni pizza casserole brings comfort food and classic Italian flavors together in one delightful dish. Cheesy layers of pasta, zesty marinara, and crispy pepperoni create a crowd-pleasing meal you’ll crave again and again.


Ingredients

Scale

Main Ingredients:

  • 1 lb ground beef
  • 8 ounces (226 grams) pasta (penne or rotini)
  • 2025 pepperoni slices

Cheese Ingredients:

  • 2 cups shredded mozzarella cheese
  • 1/2 cup grated Parmesan cheese

Sauce and Seasoning:

  • 1 jar (24 ounces / 680 grams) pizza sauce
  • 1 teaspoon Italian seasoning

Instructions

  1. Prepare the oven by heating to 375°F (190°C), ensuring even temperature distribution for optimal cooking.
  2. Boil pasta in salted water according to package instructions until al dente, then thoroughly drain and set aside.
  3. Brown ground beef in a large skillet over medium-high heat, breaking into small crumbles. Eliminate excess grease completely.
  4. Incorporate pizza sauce and Italian seasoning into the beef, simmering for 2-3 minutes to meld flavors and develop a rich, savory base.
  5. Grease a baking dish and create the first layer using half the cooked pasta, spreading evenly across the bottom.
  6. Distribute half the seasoned beef mixture over the pasta, followed by a generous layer of shredded mozzarella and cheddar cheeses.
  7. Repeat the layering process with remaining pasta, beef mixture, and cheeses to create a hearty, structured casserole.
  8. Artfully arrange pepperoni slices across the top layer, covering the entire surface for maximum flavor and visual appeal.
  9. Sprinkle Parmesan cheese over the pepperoni to add a crisp, tangy finish.
  10. Bake uncovered in the preheated oven for 20-25 minutes until the cheese melts completely and turns golden brown with crispy edges.
  11. Remove from oven and let rest for 5 minutes before serving to allow the casserole to set and flavors to intensify.

Notes

  • Swap ground beef with ground turkey or plant-based crumbles for a leaner or vegetarian version.
  • Use whole wheat pasta to boost nutritional value and add extra fiber to the dish.
  • Experiment with different cheese blends like mozzarella, provolone, or a four-cheese mix for more complex flavor profiles.
  • Add extra vegetables like diced bell peppers, mushrooms, or spinach between layers to increase nutrient density and create a more balanced meal.
  • Prep Time: 30 minutes
  • Cook Time: 25 minutes
  • Category: Lunch, Dinner, Snacks
  • Method: Baking
  • Cuisine: Italian-American

Nutrition

  • Serving Size: 6
  • Calories: 569 kcal
  • Sugar: 7 g
  • Sodium: 920 mg
  • Fat: 33 g
  • Saturated Fat: 14 g
  • Unsaturated Fat: 16 g
  • Trans Fat: 0.5 g
  • Carbohydrates: 35 g
  • Fiber: 3 g
  • Protein: 38 g
  • Cholesterol: 95 mg